Anthracycline compounds and uses thereof

Dérivés d'anthracycline et leur emploi

Anthracyclinderivate und deren Verwendung

Abstract

Disclosed is a novel anthracycline compound of the following formula (I): wherein R' and R 2 are each a hydroxyl group or a hydrogen atom and satisfy the condition that, when R 2 is a hydroxyl group, R' is a hydroxyl group or a hydrogen atom, whereas, when R 2 is a hydrogen atom, R' is a hydrogen atom, or an acid addition salt thereof. These compounds can be contained as active ingredients in antitumor agents, whereby good results are attainable.

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Patent Citations (3)

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    GB-2124224-AFebruary 15, 1984Stanford Res Inst IntDerivatives of daunorubicin and doxorubicin
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Cited By (10)

    Publication numberPublication dateAssigneeTitle
    EP-0290744-A2November 17, 1988Kirin Beer Kabushiki KaishaAnthracycline compounds and use thereof
    EP-0290744-A3December 20, 1989Kirin Beer Kabushiki KaishaAnthracycline compounds and use thereof
    EP-0349941-A2January 10, 1990BEHRINGWERKE AktiengesellschaftDérivés morpholino- de Rhodomycine, procédé pour leur préparation et leur utilisation
    EP-0349941-A3July 18, 1990BEHRINGWERKE AktiengesellschaftMorpholino-Derivate der Rhodomycine, Verfahren zu ihrer Herstellung und ihre Verwendung
    EP-0434960-A1July 03, 1991PHARMACIA S.p.A.1,5-diiodo-2-methoxy ou benzyloxy intermédiates chiraux
    EP-1323423-A1July 02, 2003Pharmacia & Italia S.p.A.Kombination Zubereitungen die Anthracyclin Derivate enthalten
    EP-1977753-A1October 08, 2008Nerviano Medical Sciences S.r.l.Préparations combinées comprenant des dérives d'anthracycline
    US-4888418-ADecember 19, 1989Kirin Beer Kabushiki KaishaDerivatives of 13-deoxycarminomycin
    US-5304687-AApril 19, 1994Farmitalia Carlo Erba S.R.L.Morpholinyl derivatives of doxorubicin and process for their preparation
    WO-9109046-A1June 27, 1991Farmitalia Carlo Erba S.R.L.Morpholinyl derivatives of doxorubicin and process for their preparation